phd defense - biotechnology: ruth amanna

ruth amanna will present her biotechnology phd research on thursday, september 4 at 1:30 pm in cb 4058.

title: induction of actinobacterial enzymes for enhanced biodegradation of polyethylene terephthalate plastics

short summary: the study addresses the environmental challenge of polyethylene terephthalate (pet) pollution using a biodegradation-based depolymerization strategy. it includes physicochemical modifications to enhance pet degradability, optimized cutinase enzyme production by thermobifida fusca yx, and in silico investigations to identify potential pet-hydrolyzing enzymes. techniques like uv photooxidation and reduced particle size improved biodegradation efficiency, with higher temperatures favoring whole-cell degradation. the optimization of cutinase production yielded a 42% increase, showcasing its potential for large-scale application. lastly, six candidate cutinase enzymes were identified for their efficacy in pet degradation, emphasizing sustainable waste management solutions.

committee members: dr. sudip kumar rakshit (supervisor), dr. baoqiang liao, dr. kang kang and dr. animesh dutta (external)

everyone is welcome

for more information contact brenda magajna at phd.ses@lakeheadu.ca