the role of free- and liposomal-n-acetycysteine in paraquat-induced cytotoxicity

dc.contributor.advisor	suntres, zacharias
dc.contributor.author	mitsopoulos, panagiotis
dc.date.accessioned	2012-11-11t02:49:54z
dc.date.available	2012-11-11t02:49:54z
dc.date.created	2009-09
dc.date.issued	2012-11-10
dc.identifier.uri	http://knowledgecommons.lakeheadu.ca/handle/2453/265
dc.description.abstract	paraquat (pq), one of the most commonly used herbicides worldwide, is hightly toxic to humans and exposure can result in severe clinical situations with no effective treatments available. the toxicity of pq has been attributed to its ability to continuously produce reactive oxygen species (ros) via redox cycling. oxidants have been shown to induce the expression of several early response genes and to activate transcription factors, which may contribute to the inflammatory response associated with pq injury.	en_us
dc.language.iso	en_us	en_us
dc.subject	paraquat	en_us
dc.subject	toxicology	en_us
dc.subject	herbicides	en_us
dc.subject	n-acetycysteine	en_us
dc.subject	cell-mediated cytotoxicity	en_us
dc.subject	liposomes	en_us
dc.subject	oxidation-reduction reaction	en_us
dc.subject	antioxidants	en_us
dc.title	the role of free- and liposomal-n-acetycysteine in paraquat-induced cytotoxicity	en_us
dc.type	thesis	en_us
etd.degree.name	m.sc.
etd.degree.level	master	en_us
etd.degree.discipline	biology	en_us
etd.degree.grantor	阿根廷vs墨西哥竞猜	en_us
dc.contributor.committeemember	khaper, neelam
dc.contributor.committeemember	law, david
dc.contributor.committeemember	malek, ladislav