a paper from our group has been published titled “image quality evaluation for a clinical organ-targeted pet camera” in frontiers in oncology (volume: 14, march 2024). congratulations on the published paper!

introduction: a newly developed clinical organ-targeted positron emission tomography (pet) system (also known as radialis pet) is tested with a set of standardized and custom tests previously used to evaluate the performance of positron emission mammography (pem) systems.
methods: imaging characteristics impacting standardized uptake value (suv) and detectability of small lesions, namely spatial resolution, linearity, uniformity, and recovery coefficients, are evaluated.
results: in-plane spatial resolution was measured as 2.3 mm ± 0.1 mm, spatial accuracy was 0.1 mm, and uniformity measured with flood field and nema nu-4 phantom was 11.7% and 8.3% respectively. selected clinical images are provided as reference to the imaging capabilities under different clinical conditions such as reduced activity of 2-[fluorine-18]-fluoro-2-deoxy-d-glucose (18f-fdg) and time-delayed acquisitions. suv measurements were performed for selected clinical acquisitions to demonstrate a capability for quantitative image assessment of different types of cancer including for invasive lobular carcinoma with comparatively low metabolic activity. quantitative imaging performance assessment with phantoms demonstrates improved contrast recovery and spill-over ratio for this pet technology when compared to other commercial organ-dedicated pet systems with similar spatial resolution. recovery coefficients were measured to be 0.21 for the 1 mm hot rod and up to 0.89 for the 5 mm hot rod of nema nu-4 image quality phantom.
discussion: demonstrated ability to accurately reconstruct activity in tumors as small as 5 mm suggests that the radialis pet technology may be well suited for emerging clinical applications such as image guided assessment of response to neoadjuvant systemic treatment (nst) in lesions smaller than 2 cm. also, our results suggest that, while spatial resolution greatly influences the partial volume effect which degrades contrast recovery, optimized count rate performance and image reconstruction workflow may improve recovery coefficients for systems with comparable spatial resolution. we emphasize that recovery coefficient should be considered as a primary performance metric when a pet system is used for accurate lesion size or radiotracer uptake assessments.

continue reading the article: https://doi.org/10.3389/fonc.2024.1268991

the post new publication: image quality evaluation for a clinical organ-targeted pet camera in frontiers in oncology appeared first on rezniklab and posted by pavlo karasyuk.

congratulations to harutyun poladyan for completing his dissertation on “organ-specific
positron emission tomography devices based on sipms” and receiving his phd! reznik’s group
wishes you well and are excited to bless you in your future endeavors.

the post congratulations: harutyun poladyan on a completed phd! appeared first on rezniklab and posted by pavlo karasyuk.

this graduate student research conference 2017 was held in 阿根廷vs墨西哥竞猜 agora during research and innovation week in march 2017. this conference was organised by the faculty of graduate studies. at this year’s conference, more than 20 posters were presented by the graduate 世界杯2022赛程表淘汰赛  from various departments of 阿根廷vs墨西哥竞猜 .

entire reznik research group congratulates the participant and wishes him good luck!

the post congratulation to harutyun poladyan – winner of graduate poster competition at 阿根廷vs墨西哥竞猜 appeared first on rezniklab and posted by pavlo karasyuk.