date: september 16, 2024

congratulations to anirudh on the successful defense of his msc thesis in physics. anirudh presented his work titled ‘evaluation of multi-angle imaging with planar organ-targeted positron emission tomography detectors‘ conducted under the supervision of dr. alla reznik. the reznik group wishes him all the best as he embarks on his phd studies.

congratulations once again!

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a paper from our group has been published titled “image quality evaluation for a clinical organ-targeted pet camera” in frontiers in oncology (volume: 14, march 2024). congratulations on the published paper!

introduction: a newly developed clinical organ-targeted positron emission tomography (pet) system (also known as radialis pet) is tested with a set of standardized and custom tests previously used to evaluate the performance of positron emission mammography (pem) systems.
methods: imaging characteristics impacting standardized uptake value (suv) and detectability of small lesions, namely spatial resolution, linearity, uniformity, and recovery coefficients, are evaluated.
results: in-plane spatial resolution was measured as 2.3 mm ± 0.1 mm, spatial accuracy was 0.1 mm, and uniformity measured with flood field and nema nu-4 phantom was 11.7% and 8.3% respectively. selected clinical images are provided as reference to the imaging capabilities under different clinical conditions such as reduced activity of 2-[fluorine-18]-fluoro-2-deoxy-d-glucose (18f-fdg) and time-delayed acquisitions. suv measurements were performed for selected clinical acquisitions to demonstrate a capability for quantitative image assessment of different types of cancer including for invasive lobular carcinoma with comparatively low metabolic activity. quantitative imaging performance assessment with phantoms demonstrates improved contrast recovery and spill-over ratio for this pet technology when compared to other commercial organ-dedicated pet systems with similar spatial resolution. recovery coefficients were measured to be 0.21 for the 1 mm hot rod and up to 0.89 for the 5 mm hot rod of nema nu-4 image quality phantom.
discussion: demonstrated ability to accurately reconstruct activity in tumors as small as 5 mm suggests that the radialis pet technology may be well suited for emerging clinical applications such as image guided assessment of response to neoadjuvant systemic treatment (nst) in lesions smaller than 2 cm. also, our results suggest that, while spatial resolution greatly influences the partial volume effect which degrades contrast recovery, optimized count rate performance and image reconstruction workflow may improve recovery coefficients for systems with comparable spatial resolution. we emphasize that recovery coefficient should be considered as a primary performance metric when a pet system is used for accurate lesion size or radiotracer uptake assessments.

continue reading the article: https://doi.org/10.3389/fonc.2024.1268991

the post new publication: image quality evaluation for a clinical organ-targeted pet camera in frontiers in oncology appeared first on rezniklab and posted by pavlo karasyuk.

date: november 12, 2023

we are pleased to inform you that anirudh shahi and dr. oleksandr bubon attended the 2023 ieee nuclear science symposium and medical imaging conference and room temperature semiconductor detector conference in vancouver, from november 4 – 11.

anirudh presented a poster titled “multi-angle image reconstruction method for a planar organ targeted pet detector”. dr. bubon presented a poster with the following title: “performance evaluation of a high-sensitivity organ-targeted positron emission tomography (pet) system for small lesion detection and quantitative imaging”. more information about the conference and other presentations can be found here.

the post ieee 2023 nss mic rtsd conference attendance appeared first on rezniklab and posted by pavlo karasyuk.

date: november 15, 2022

we are pleased to inform you that oleksandr grynko, brandon baldassi, and borys komarov attended the 2022 ieee nuclear science symposium and medical imaging conference and room temperature semiconductor detector conference in milan, italy, from november 5-12.

oleksandr presented an oral presentation titled “amorphous lead oxide based multilayer x-ray detector with near-theoretical sensitivity.” brandon and borys each presented posters with the respective titles: “low-dose imaging performance of a clinical organ-targeted positron emission tomography (pet) camera” and “application of gpu-based reconstruction for a clinical organ-targeted pet scanner.” more information about the conference and other presentations can be found here.

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the post dr. alla reznik receives more than $448k from the canadian cancer society appeared first on rezniklab and posted by pavlo karasyuk.

radialis medical’s medical chief technology officer, sasha bubon, was presented mitacs nrc irap award for commercialization for his astounding efforts and accomplishments in developing a lower-dose pet device for high-resolution imaging mammography. more information.

the post congratulations to sasha bubon on mitacs nrc irap award for commercialization appeared first on rezniklab and posted by pavlo karasyuk.