the indigenous gender and wellness development grant funding opportunity is expected to:

• support planning activities that establish priorities for indigenous-led research projects related to gender and wellness;
• facilitate relationship building, knowledge sharing and learning that develop and strengthen indigenous-led, community-based projects; and
• support the continued development of ideas and plans to implement action-oriented, community-based projects that will improve wellness among indigenous communities from a gendered perspective.

the 2019 early career investigator awards in circulatory and respiratory health are expected to:

• increase canada’s research capacity in the areas of circulatory and respiratory research;
• support the early research career of promising circulatory and respiratory scientists; and
• support circulatory and respiratory health research by and with indigenous peoples

the cihr dementia research strategy supports research on the latest preventive, diagnostic and treatment approaches to alzheimer's disease and other neurodegenerative diseases causing dementia. it consists of an international and a national component, which together, allows the government of canada to support world-class research on dementia, contributing to the global pursuit of finding a cure or disease-modifying treatment for dementia by 2025.

the canadian consortium on neurodegeneration in aging (ccna) is the canadian component of the cihr dementia research strategy representing the center of excellence for canada. ccna is the premier research hub for all aspects of research involving neurodegenerative diseases that affect cognition in aging – including alzheimer's disease.

the network of centres of excellence in neurodegeneration (coen) is an international initiative, which will connect centers of excellence (coes) with a critical mass of resources and expertise to drive a step-change in neurodegeneration research. as such, the lead canadian principal applicant for this funding opportunity must be a ccna member. it is expected that teams will combine the research strengths across coes in at least two partner countries to provide a true value-added collaborative effort that will advance our approach to neurodegeneration research. projects will address issues which would not readily be funded through the standard grant mechanisms of the coen partners, and it is expected that in addition to collaboration across coes, projects should also serve to provide a platform for future collaboration with industry.

this funding opportunity seeks to address the need for innovative research to underpin new approaches to therapeutic intervention. the call sets out to encourage “outside the box” thinking, to stimulate new and unconventional approaches and creative solutions to the challenges of neurodegeneration research by undertaking high-risk / high-payoff research.

for more information, please consult the centres of excellence in neurodegeneration (coen) website.

the partnerships for cannabis policy evaluation funding opportunity is expected to:

• evaluate cannabis-related policies at the level of provincial/territorial jurisdictions and indigenous communities;
• support cannabis-related research relevant to decision makers by producing results that can be applied to multiple regions and/or settings;
• generate evidence on the positive and negative health, and public safety impacts of cannabis-related policies across canada;
• support cross-jurisdictional comparisons of cannabis-related policies;
• identify best practices in near–real time through cannabis-related data and knowledge sharing;
• support disaggregation of data by sub-population(s) (e.g. youth), and by biological and social determinants of health, including sex as a biological variable and gender as a sociocultural determinant of health; and
• develop multi-team, cross-jurisdictional collaborations that will support cannabis-related data interoperability, harmonization and sharing, and knowledge translation.

the specific objectives of the team grant: pathways implementation research team component 3 are to:

• increase the equitable reach, access and sustainability of culturally appropriate population health interventions using an implementation science approach
• develop and share recommendations, guidelines and policies for sustainability and enhanced equitable reach and access of interventions that incorporates reciprocal learning between participating indigenous communities and research teams
• build capacity for implementation research in indigenous communities by training and mentoring junior researchers through partnerships with communities, including 世界杯2022赛程表淘汰赛 and trainees with indigenous living experience, and community members.

the objectives of this funding opportunity are to:

• support the development, validation, harmonization and optimization of standardized methods, protocols, data collection and reporting standards as well as statistical techniques to study sex as a variable in basic cellular, tissue, and animal research at critical developmental periods including old age across broad research domains;
• advance our understanding of basic mechanisms that drive sex differences across the lifespan;
• support capacity building in age- and sex-related scientific techniques and grow the science among the next generation of health researchers; and
• promote knowledge dissemination of standardized methods, protocols and techniques.

this funding opportunity is expected to:

• support world leading collaborative research teams aimed at tackling diabetes.
• enhance existing partnerships and develop new partnerships between the uk and canada in the area of diabetes research.
• strengthen the strategic relationship between the uk and canada.

the understanding disease prevention and risk factor modification catalyst grants are expected to:

• increase our understanding of factors that enable individuals to adopt or overlook known disease risk modification strategies;
• expand the evidence and further understanding that can lead to future intervention studies in prevention; and
• develop a knowledge base upon which to nuance evidence-based policy to improve the prevention of manageable diseases.

the strategy for patient-oriented research (spor) is a national coalition of federal, provincial and territorial partners (patients and informal caregivers, health authorities, academic health centres, charities, philanthropic organizations, private sector, etc.) dedicated to the integration of research into care.

patient-oriented research, which is foundational to evidence-informed health care, refers to a continuum of research that engages patients as partners, focusses on patient-identified priorities and improves patient outcomes. this research, conducted by multidisciplinary teams in partnership with relevant stakeholders, aims to apply the knowledge generated to improve healthcare systems and practices.

the vision for spor is that canada will demonstrably improve health outcomes and enhance the health care experience for patients through the integration of evidence at all levels of the health care system.

innovative clinical trials initiative

the spor innovative clinical trials (ict) initiative contributes to increasing canadian competitiveness in ict research and provides a stimulus for trialists to adopt new methodologies, enhance patient and clinician engagement in research, and build capacity and increase the intensity of ict research. icts use non-traditional designs that are alternative to traditional randomized controlled trials (rcts), with application in areas ranging from product development to health system improvement. ict methods reduce the cost of conducting trials, reduce the amount of time needed to answer research questions, and increase the relevance of research findings to patients, healthcare providers and/or policy makers. adopting these alternative designs can maximize the use of existing knowledge and data.

research areas

spor icts need to have a primary focus in the research areas of:

comparative effectiveness research:

comparative effectiveness research compares two or more healthcare options already shown to be efficacious. the healthcare options could include diagnostics, drugs, medical devices, surgeries, complementary medicine, self-care or ways to deliver health care. the findings should be able to inform healthcare decisions by providing evidence on the effectiveness, benefits, and harms of different healthcare options and other types of interventions; and/or

implementation science research: implementation science research examines interventions that are already shown to work under certain conditions and within certain contexts, which could be defined by demographic, biological, clinical, social, economic, geographic, or other factors. the interventions could include diagnostics, drugs, medical devices, surgeries, complementary medicine, self-care or ways to deliver health care. implementation science aims to determine if these interventions can be adapted to other contexts, how should they be adapted and what are the longer term effects.  in other words, implementation research seeks to understand what interventions work for whom and under what circumstances. it studies the factors that influence the full and effective use of interventions in practice, which could include affordability, adaptability, sustainability and equitable scalability.

application requirements

to meet the requirements of the funding opportunity, the following elements must be included as part of an application:

• the proposed research activities must be patient-oriented in that:
  • patients are engaged as partners;
  • there is a focus on patients’ priorities;
  • the aim is to improve patient outcomes;
  • the work is conducted by a multi-disciplinary team that includes patients;
  • there is involvement of other spor stakeholders such as policy makers, health care professionals and health charities; and
  • research findings can be applied to health care or policy.
• the proposed research must be an ict as described above.
• applicants must focus on comparative effectiveness research and/or implementation science research as described above.
• applicants are required to explore collaborations with the spor support units, the spor canadian data platform, and the spor evidence alliance to strengthen their application and support the research project.

this funding opportunity is expected to:

• support the creation and/or further development of formal networks by encouraging national and international collaboration, resource sharing, capacity building and dissemination in priority research areas;
• identify and establish novel connections across canada. this will bring together a collaborative multidisciplinary group of technical and scientific experts;
• develop and strengthen research capacity by connecting and engaging current researchers and training the next generation of researchers;
• develop and provide health research leadership across canada, linking to related international initiatives (as appropriate);
• facilitate translation of new knowledge generated by research evidence; and
• ensure patient engagement to increase the outcomes and health impacts for canadians.