objectives: xstrata is a global diversified mining group whose businesses maintain a meaningful position in seven major international commodity markets, including those of copper and nickel, with a large cohort of nickel workers employed in the province of ontario, canada at sudbury in northeastern ontario. operating since 1929, sudbury operations have historically included underground, milling, and smelting related to the production of nickel, copper, cobalt and other precious metals. the objective for this study is to: follow-up and examine cancer incidence and mortality for various diseases in this occupational cohort methods: this study will describe a retrospective occupational cohort study of mortality (1964-2001) and cancer incidence (1964-2001) conducted for xstrata nickel’s ontario male nickel workers (n= 10,253 males). the cohort was originally assembled by researchers at mcmaster university, with responsibility transferred, to the northeastern ontario regional cancer centre of the sudbury regional hospital in the late 1990s. company nominal role and work history information were linked to provincial health data at cancer care ontario. given minimal out of province migration, using the ontario population as a reference, standardized mortality ratios for a wide variety of diseases and standardized cancer incidence ratios were calculated overall, by start decade, by work area, by duration of employment, and by work area and duration of employment and by work area and start decade. results: in the cohort of male workers, there were 1,984 (19.35%) deaths and 1,127 (10.99%) incident cancers. while the results reflected very few significantly high sers or smrs, notable data was observed in deaths resulting from accidents, poisonings, or violence as both workers with less than 15 years since first hire (sir=133,95% cl: 111-158) and workers with 15 or more years since first hire (sir=123,95% cl: 104-144) displayed significantly high results. notable data was also seen in workers with less than 15 years since first hire, with smrs for rail, road, or air (smr=136,95% cl: 102-177) and possibly job-related (smr=241, 95% cl: 159-351) significantly high. conclusions: there was no significant overall increase displayed for cancer incidence. overall mortality displayed significant increases in deaths resulting from accidents, poisonings, or violence as well as deaths resulting firom rail, road, or air.