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    theory and production of hyperpolarized xenon gas

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    fittermana2015m-1b.pdf (1.925mb)
    date
    2015-12-03
    author
    fitterman, avner
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    abstract
    conventional magnetic resonance imaging (mri) modality is based on the magnetization that is formed by the influence of a strong polarizing magnetic field on the spin of protons, typically those of water molecules within the body. in hyperpolarized (hp) gas mri, a dramatic increase in spin polarization is achieved using spin-exchange optical pumping (seop), which allows images to be obtained with a high signal-to-noise ratio (snr). batch-mode custom-built polarizers can serve to produce the hp gas, however, such custom-built systems require optimization in terms of pressure and temperature parameters. this study is comprised of three objectives: i) gaining understanding regarding the physics of the nuclear polarization process of 129xe; ii) examining experimentally the pressure and temperature dependences of the polarization, similarly to the way it was done in previous studies; iii) exploiting this knowledge for the benefit of the optimization of the custom-built polarizer in our lab.
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    http://knowledgecommons.lakeheadu.ca/handle/2453/686
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