about the cihr transitions in care multi-institute initiative

the goal of the transitions in care (tic) multi-institute initiative is to improve the health and wellness of canadians by supporting research that transforms the health system to optimize the outcomes of patients experiencing transitions in care.

about the evaluation grants

this funding opportunity is part of the tic initiative. this competition will support the rigorous evaluation of implemented activities such as interventions, tools, practices, policies, technologies, programs and/or other solutions that address transitions in care challenges. the focus of the evaluation grants is to support researchers and knowledge users to formally evaluate, validate and/or demonstrate the effectiveness, appropriateness and/or impact of implemented transitions in care activities to create high-quality, real-world evidence, relevant to transitions in care, overall health and/or health system improvement. research activities can be nationally, provincially or municipally managed and may include, but are not limited to, comparative policy analysis, cost-effectiveness analysis, and guideline and program evaluation.

research areas

this funding opportunity will support applications centered on the intersection of two or more tic focus areas. 

tic focus areas

1. across life’s trajectories: transitioning through life’s trajectories (e.g., infant to child, child to youth, youth to adult or adult to older adult and beyond) necessitates changes in the source and nature of the services provided that are challenging to navigate, create anxiety and/or expose patients to known care gaps that could lead to poor, yet avoidable, outcomes.
2. changing health status or care: individuals facing changes in their health status or living with chronic or complex health conditions may visit their primary care physician, be referred to specialists, be assessed in an emergency department, be admitted to hospital, require surgery, move to a rehabilitation facility, and/or become disabled and not be capable of returning to their previous place of residence.  these individuals experience exchange among health providers, care settings, institutions, and/or hospital units (e.g., urban vs rural; hospital vs home; tertiary care vs community care).
3. key populations to optimize transition outcomes: populations at increased risk of adverse transition outcomes include: first nations, inuit and métis peoples; individuals from rural and remote communities, individuals who identify as transgender; individuals with an intersex condition, older adults, new aging populations (i.e. survivors of diseases/conditions that previously led to early death); new immigrants to canada and those who experience systemic, cultural and/or language barriers.

description

the goal of the sepsis research network initiative (the network) is to fund a single nationally coordinated research network to further understand the causes and improve the prevention, detection and management of sepsis. the network will bring together experts from different disciplines working collaboratively on a number of inter-related research projects under an integrated and unified program of research.

application requirements

applications must outline two or more collaborative research projects which address different aspects of sepsis research that contribute to the goals of the overall program of research; as well as an administrative core that is responsible for the coordination and oversight of all aspects of the program, including the cross-cutting components. one of the collaborative projects must focus on research to better understand the increased risk of mortality due to sepsis in people with diabetes and how to prevent it and/or how nutrition may play a role in the treatment of sepsis.

research projects may vary in terms of their size, complexity and cost, and should benefit from the scientific expertise of multiple members of the team. to ensure teams are well positioned to generate new knowledge and apply it in a timely fashion, research activities must include appropriate and diverse stakeholders and partners, bringing together experts from different disciplines (e.g., allied health professionals, first responders, emergency medicine, primary care, community care), sectors (e.g. industry, government, patient groups, health providers and not-for-profit organizations) and all four cihr research themes.

applicants to this initiative are also required to undertake primary prevention and ethics research relevant to sepsis. in the context of this funding opportunity, ethics research is understood as applied to health and health care research and may entail theoretical inquiries or empirical investigations of ethics issues. applicants that undertake ethics research associated with the network may do so by, for example:

• engaging a post-doctoral fellow in the area of research in ethics (as it relates to health, health research and/or health policy) to conduct a critical analysis of the research topic
  • including a researcher in ethics (as it relates to health, health research and/or health policy) as a collaborator or applicant to study the ethical implications of sepsis
• engage patients as partners in order to help improve patient outcome, healthcare systems and practices

in order for network research activities to benefit all canadians, applicants must outline how they will account for sex (as a biological variable) and gender, as well as other socio-cultural factors. addressing equity, diversity and inclusion strengthens the scientific community and the quality, social relevance and impact of the research. inclusion of diversity and gender equity in the research enterprise are key priorities of cihr’s equity strategy. as such, applicants are to describe any planned approaches to promote an inclusive research and work environment in the research design, methods, analysis and interpretation, and/or dissemination of findings, such as efforts to increase participation from under-represented and/or minority groups, and any considerations of equity, diversity and inclusion in the recruitment practices and training/mentorship activities. applicants are encouraged to complete the cihr unconscious bias learning module and visit cihr’s sex, gender and health research page for more information and resources.

governance

it is expected that the network will develop a governance structure that includes a network steering committee (committee), led by the nominated principal applicant (npa) and representation from all of the research teams (teams), each led by a principal applicant (pa). in addition, at least one patient representative from the sepsis community must be included as a member of the committee. the network is expected to include a minimum of three teams. the roles and responsibilities of the npa and pas are as follows:

nominated principal applicant

the npa will lead the committee and will be responsible for the oversight of the research program, achieving the objectives of the network, overseeing the governance and collaborative synergistic activities to optimize the impact of research on the health of canadians.

in collaboration with the pas and the committee, the npa will be responsible for:

• the synergistic activities within the teams as well as implementation of the cross-cutting components of the network including:
• capacity building: a single, cohesive training, mentoring and early-career investigator plan that spans across and engages all teams.
• equity: recognizing that equity is an integral part of a sustainable health research ecosystem, the npa must be committed to supporting and promoting cihr’s equity strategy across the network by ensuring equitable and transparent research and work environments.
• data management: aligning with the cihr health research and health-related data framework and action plan, the npa is expected to coordinate the collection, use and management of data collected across the teams.
• knowledge exchange: engaging in knowledge exchange activities committed to transforming existing and new knowledge generated into better care policies, practices, procedures, products and services for sepsis care across canada.  
• management of patient complexity: many patients who develop sepsis have complex medical issues (e.g., frailty, obesity, diabetes, cardio-respiratory conditions, etc.) that contribute to poorer outcomes and the need for additional interventions (e.g., nutrition, dialysis, ecmo, etc.). understanding the associations and improving outcomes should be a consideration in all teams.
• the npa will be responsible for leading the mid-term and final reports on network progress and cross-cutting components in collaboration with the pas.

principal applicants

the pas will be responsible for ensuring that the research program is carried out within each team and providing opportunities for knowledge exchange and transfer within and across the network.

the pas will be responsible for:

• providing the leadership to undertake innovative and impactful research and knowledge exchange in collaboration with all relevant stakeholders and interdisciplinary world leaders in the field, as described in the reviewed application.
• allocation of budget regarding the shared resources across their team as described in the reviewed application.
• collaborating with the npa to provide team-specific budgetary and scientific reporting to cihr;
• active participation in cross-cutting components of the network as described above.
• establishing an inclusive, equitable and rich learning environment for 世界杯2022赛程表淘汰赛 and early career investigators, as appropriate.

research areas

this funding opportunity will support a network relevant to the following research areas:

• understanding the pathogenesis, causes and possible prevention of sepsis;
• improving the prevention, detection and management of sepsis;
• understanding the roles diabetes mellitus and glucose control have on outcomes in patients with sepsis; and
• understanding the roles metabolism and nutrition may play in the treatment and outcomes for patients with sepsis.

this award is intended to:

• recognize the excellence of canadian research and innovative knowledge translation (kt) initiatives of graduate 世界杯2022赛程表淘汰赛 (e.g. m.d., m.a., m.sc. and ph.d.) and post-doctoral fellows studying health services and policy research;
• recognize research and/or kt contributions for which a graduate student or post-doctoral fellow has had primary responsibility; and
• promote careers in health services and policy research.

this award is intended to recognize published research in a peer-reviewed journal that has significantly contributed to the advancement of the field of health services and policy research in canada. ihspr will consider articles related to:

• research that demonstrates a clear impact or potential impact on policy, practice, or health outcomes (e.g., decision maker uptake, change management for improved practice);

  or

• research that breaks ground in the way health services or policy research is conducted (e.g., innovations in methodology, novel theory or application of theory, new approaches to existing problems).

in collaboration with canada’s research and policy communities, mitacs has established the canadian science policy fellowship. the first initiative of its kind in canada, fellowship is made possible thanks to the government of canada and participating government offices; the government of british columbia and participating government offices; the university of ottawa’s institute for science, society and policy; professor sarah otto, department of zoology, university of british columbia; the university of victoria; and the canadian science policy fellowship advisory council. participating hosts for the fellowship include host offices from the governments of canada and british columbia, and quebec.

the fellowship aims to:

• form mutually beneficial relationships between government decision makers and academic researchers in support of policy challenges in canada
• enhance science communication, collaboration, and policy capacity in government offices
• contribute to evidence-informed decision making in canada’s public service
• create a national network of expertise among academic researchers fostering public policy contributors across academia, government, not-for-profit organizations, and industry

fellowship activities

the fellowship provides a 12-month immersion into the policy-making process. working in host offices with government decision makers and stakeholders, fellows contribute their academic expertise and analytical skills to inform policy actions. fellows’ participation in policy activities provides them with the direct training and experience to address challenges of national public importance.

during the fellowship, mitacs and its partners provide professional development, skill-building, and networking events, which will enhance fellows’ policy-related knowledge and capabilities and expand their networks. mitacs instructor-led courses are mandatory and focus on developing two central themes: increasing awareness of canadian public policy (federal and/or provincial), and strengthening communication and relationship building skills with diverse stakeholders, including government and academia.

the tanaka fund was established in 1974 as the result of an exchange of gifts between the governments of canada and japan. canada offered $1,000,000 to japan to promote canadian studies in japanese universities, while japan provided 300 million yen for the enhancement of japanese studies in canadian universities. the funds were used to establish the “japan foundation trust fund for the promotion of japanese studies in canadian universities”.

guidelines developed by the japan foundation stipulated that the trust fund would be administered as an endowment and that the income thereof should be made available for the support and promotion of japanese studies at universities and colleges in canada. universities canada has administered the fund since 1975.

until 2016, support for japanese language lectureship at canadian universities was funded. in 2018, the tanaka fund was restructured to focus support towards young emerging scholars in order to foster the next generation of japanese studies scholarship in canada.

annual value: a total of $30,000 is available for this year’s awards.

value of grants: grants up to a maximum of $10,000 are available

who is eligible: masters or doctoral level 世界杯2022赛程表淘汰赛

duration: a maximum of three months in japan

application deadline: january 6, 2019

the fy19 defense appropriations act provides $10 million (m) to the department of defense amyotrophic lateral sclerosis research program (alsrp) to support innovative and high-impact research into preclinical development of therapeutics for amyotrophic lateral sclerosis.  as directed by the office of the assistant secretary of defense for health affairs, the defense health agency (dha), j9 research and development directorate manages the defense health program (dhp) research, development, test and evaluation (rdt&e) appropriation.  the managing agent for the program announcements/funding opportunities is the congressionally directed medical research programs (cdmrp).

the mission of the alsrp is to fund innovative preclinical research to develop new treatments for als for the benefit of service members, veterans, and the general public.

https://cdmrp.army.mil/funding/alsrp

the following mechanisms have been released:

therapeutic development award – preproposal due by 3/22/19

• ·         independent investigators at all academic levels
• ·         pre-application is required; full application submission is by invitation only
• ·         supports post-discovery, preclinical development of therapeutics for als
• ·         preliminary data, including identity and purity of an identified bioactive compound(s), are required
• ·         therapeutically relevant marker option available
• ·         collaboration with industry is encouraged
• ·         clinical trials are not allowed
• ·         maximum funding of $1.0 million for direct costs (plus indirect costs); $1.25 million for direct costs (plus indirect costs) for applications including the therapeutic relevant marker option
• ·         maximum period of performance is 2 years

therapeutic idea award – preproposal due by 3/22/19

• ·         independent investigators at all academic levels
• ·         maximum period of performance is 2 years

• pre-application is required; full application submission is by invitation only
• supports screening methods or new ideas aimed at als drug or treatment discovery still in the early stages of development
• preliminary data are not required
• not intended to support projects focusing on the pathophysiology of als
• maximum funding of $500,000 for direct costs (plus indirect costs)

a pre-application is required and must be submitted through the electronic biomedical research application portal (ebrap) athttps://ebrap.org prior to the pre-application deadline.  all applications must conform to the final program announcements and general application instructions available for electronic downloading from the grants.gov website.  the application package containing the required forms for each award mechanism is also on grants.gov.  a listing of all cdmrp funding opportunities can be obtained on the grants.gov website by performing a basic search using cfda number 12.420.

applications must be submitted through the federal government’s single-entry portal, grants.gov.  for email notification when program announcements are released, subscribe to program-specific news and updates under “email subscriptions” on the ebrap homepage athttps://ebrap.org.  for more information about the alsrp or other cdmrp-administered programs, please visit the cdmrp website (http://cdmrp.army.mil).

point of contact:

cdmrp help desk

301-682-5507 
help@ebrap.org

book mark the cdmrp website:

cdmrp.army.mil